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The Penn Vector Core is a full-service viral vector core facility located on the University of Pennsylvania's campus. With more than a decade of experience in the production of viral-based vectors, the Core has become an important technological resource for investigators interested in the use of viral-based vectors for gene transfer within and external to Penn.
The Core's main objective is to provide investigators access to state-of-the-art vector technology for preclinical studies and other basic research applications. Such studies, utilizing carefully designed viral vectors, can provide information critical to the understanding of gene function and the development of therapeutic vectors.
The Penn Vector Core specializes in the provision of novel AAV serotype vectors, and has the greatest experience in producing novel serotype vectors developed at Penn. AAV 1, 7, 8, 9, and rh10 were originally isolated at Penn in the laboratory of Dr. James M. Wilson and first made available to investigators through the Penn Vector Core. Due to its close proximity to the Wilson laboratory, the Core can rapidly assimilate new vector technologies and make them available to its users. In addition to these serotypes, we also offer manufacturing of AAV2, AAV5, AAV6, AAV6.2, rh10, hu11, and the PHP variants (PHP.B, PHP.eB, PHP.S).
The Core offers a variety of novel serotype AAV vectors, and additional vectors currently under development will be distributed through the Penn Vector Core. All of the vectors generated by the Penn Vector Core are distributed under material transfer agreements (MTA) to academic, government, and non-profit institutions.
The Penn Vector Core is pleased to partner with Addgene to provide greater access to high-quality AAV vectors for the research community. Our inventory vectors have now been added to Addgene’s catalog. If you don't find your vector of interest at Addgene, please contact us.
The Penn Vector Core will continue to produce the same high-quality viral vectors for distribution through Addgene as well as continue to provide custom vector production services to researchers worldwide.
We are happy to answer any questions you may have about placing a new order or checking the status of an existing order.
Penn Vector Core
125 South 31st St., Suite 2000
Philadelphia, PA 19104-3403