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The Wilson Lab

At the heart of gene therapy discovery research, the Wilson Lab focuses on the development of next-generation gene transfer vectors and their application in the treatment of a variety of acquired and inherited diseases.

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James M. Wilson, MD, PhD

  • Director, Gene Therapy Program
  • Rose H. Weiss Professor and Director, Orphan Disease Center
  • Professor of Medicine and Pediatrics, Department of Medicine

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Affiliated Faculty

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maria limberis

Maria P. Limberis, PhD

  • Research Director, Cystic Fibrosis and Infectious & Ocular Diseases
  • Director, Program of Excellence in Cystic Fibrosis, Orphan Disease Center
  • Faculty Advisor, Program for Comparative Medicine
  • Research Associate Professor, Department of Medicine

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mingyao li square

Mingyao Li, PhD

  • Director, Biostatistics Core
  • Professor of Biostatistics, Department of Biostatistics, Epidemiology & Informatics

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lili wang headshot

Lili Wang, PhD

  • Research Director, Discovery Research and Gene Editing
  • Research Associate Professor, Department of Medicine

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Penn Biomedical Graduate Studies

Cell & Molecular Biology (CAMB) Graduate Group

The University of Pennsylvania's School of Medicine provides graduate level education in modern cell and molecular biology that prepares outstanding students for leadership careers in biomedical research. 

About CAMB

Rotations and Thesis Research in the Wilson Lab

Potential Rotation Projects:

  • Structural biology of AAV capsids
  • Engineering of AAV capsids to improve vector performance
  • Biology of AAV immunology in mice and monkeys
  • Application of AAV vectors for treatment of animal models of human genetic diseases
  • Biology of persistence of endogenous adenoviruses in nonhuman primates.
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