An AAV vector-mediated gene delivery approach facilitates reconstitution of functional human CD8+ T cells in mice.
Huang J, Li X, Coelho-dos-Reis JG, Wilson JM, Tsuji M
AAV8 induces tolerance in murine muscle as a result of poor APC transduction, T cell exhaustion, and minimal MHCI upregulation on target cells.
Mays LE, Wang L, Lin J, Bell P, Crawford A, Wherry EJ, Wilson JM
Molecular Therapy : The Journal Of The American Society Of Gene Therapy
The first journal on human gene therapy celebrates its 25th anniversary.
Human Gene Therapy