We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 11/01/2011

Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors.

Wang L, Calcedo R, Bell P, Lin J, Grant RL, Siegel DL, Wilson JM

Human Gene Therapy

Publication 11/01/2011

Inverse zonation of hepatocyte transduction with AAV vectors between mice and non-human primates.

Bell P, Wang L, Gao G, Haskins ME, Tarantal AF, McCarter RJ, Zhu Y, Yu H, Wilson JM

Molecular Genetics And Metabolism

Publication 11/01/2011

AAV8-mediated hepatic gene transfer in infant rhesus monkeys (Macaca mulatta).

Wang L, Bell P, Lin J, Calcedo R, Tarantal AF, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 10/01/2011

Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.

Flotte TR, Trapnell BC, Humphries M, Carey B, Calcedo R, Rouhani F, Campbell-Thompson M, Yachnis AT, Sandhaus RA, McElvaney NG, Mueller C, Messina LM, Wilson JM, Brantly M, Knop DR, Ye GJ, Chulay JD

Human Gene Therapy

Publication 10/01/2011

Muscle-directed gene therapy for hemophilia B with more efficient and less immunogenic AAV vectors.

Wang L, Louboutin JP, Bell P, Greig JA, Li Y, Wu D, Wilson JM

Journal Of Thrombosis And Haemostasis : Jth

Publication 9/01/2011

Adeno-associated virus antibody profiles in newborns, children, and adolescents.

Calcedo R, Morizono H, Wang L, McCarter R, He J, Jones D, Batshaw ML, Wilson JM

Clinical And Vaccine Immunology : Cvi