We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 12/01/2010

Efficient gene transfer into the mouse lung by fetal intratracheal injection of rAAV2/6.2.

Carlon M, Toelen J, Van der Perren A, Vandenberghe LH, Reumers V, Sbragia L, Gijsbers R, Baekelandt V, Himmelreich U, Wilson JM, Deprest J, Debyser Z

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 10/19/2010

Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.

Kassim SH, Li H, Vandenberghe LH, Hinderer C, Bell P, Marchadier D, Wilson A, Cromley D, Redon V, Yu H, Wilson JM, Rader DJ

Plos One

Publication 10/01/2010

Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale.

Lock M, Alvira M, Vandenberghe LH, Samanta A, Toelen J, Debyser Z, Wilson JM

Human Gene Therapy

Publication 10/01/2010

Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing.

Vandenberghe LH, Xiao R, Lock M, Lin J, Korn M, Wilson JM

Human Gene Therapy

Publication 1/01/2010

Systematic evaluation of AAV vectors for liver directed gene transfer in murine models.

Wang L, Wang H, Bell P, McCarter RJ, He J, Calcedo R, Vandenberghe LH, Morizono H, Batshaw ML, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 1/01/2010

The pleiotropic effects of natural AAV infections on liver-directed gene transfer in macaques.

Wang L, Calcedo R, Wang H, Bell P, Grant R, Vandenberghe LH, Sanmiguel J, Morizono H, Batshaw ML, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy