We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 12/01/2010

Efficient gene transfer into the mouse lung by fetal intratracheal injection of rAAV2/6.2.

Carlon M, Toelen J, Van der Perren A, Vandenberghe LH, Reumers V, Sbragia L, Gijsbers R, Baekelandt V, Himmelreich U, Wilson JM, Deprest J, Debyser Z

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 12/01/2010

α-Fetoprotein gene delivery to the nasal epithelium of nonhuman primates by human parainfluenza viral vectors.

Zhang L, Limberis MP, Thompson C, Antunes MB, Luongo C, Wilson JM, Collins PL, Pickles RJ

Human Gene Therapy

Publication 11/01/2010

New candidate vaccines against blood-stage Plasmodium falciparum malaria: prime-boost immunization regimens incorporating human and simian adenoviral vectors and poxviral vectors expressing an optimized antigen based on merozoite surface protein 1.

Goodman AL, Epp C, Moss D, Holder AA, Wilson JM, Gao GP, Long CA, Remarque EJ, Thomas AW, Ammendola V, Colloca S, Dicks MD, Biswas S, Seibel D, van Duivenvoorde LM, Gilbert SC, Hill AV, Draper SJ

Infection And Immunity

Publication 10/19/2010

Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.

Kassim SH, Li H, Vandenberghe LH, Hinderer C, Bell P, Marchadier D, Wilson A, Cromley D, Redon V, Yu H, Wilson JM, Rader DJ

Plos One

Publication 10/01/2010

Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale.

Lock M, Alvira M, Vandenberghe LH, Samanta A, Toelen J, Debyser Z, Wilson JM

Human Gene Therapy

Publication 10/01/2010

Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing.

Vandenberghe LH, Xiao R, Lock M, Lin J, Korn M, Wilson JM

Human Gene Therapy