A new genetic vaccine platform based on an adeno-associated virus isolated from a rhesus macaque.
Lin J, Calcedo R, Vandenberghe LH, Bell P, Somanathan S, Wilson JM
Journal Of Virology
Adeno-associated virus-mediated gene transfer to nonhuman primate liver can elicit destructive transgene-specific T cell responses.
Gao G, Wang Q, Calcedo R, Mays L, Bell P, Wang L, Vandenberghe LH, Grant R, Sanmiguel J, Furth EE, Wilson JM
Human Gene Therapy
Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins.
Mays LE, Vandenberghe LH, Xiao R, Bell P, Nam HJ, Agbandje-McKenna M, Wilson JM
Journal Of Immunology