We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 6/10/2001

Differences in the human and mouse amino-terminal leader peptides of ornithine transcarbamylase affect mitochondrial import and efficacy of adenoviral vectors.

Ye X, Zimmer KP, Brown R, Pabin C, Batshaw ML, Wilson JM, Robinson MB

Human Gene Therapy

Publication 6/01/2001

Biology of E1-deleted adenovirus vectors in nonhuman primate muscle.

Zoltick PW, Chirmule N, Schnell MA, Gao GP, Hughes JV, Wilson JM

Journal Of Virology

Publication 5/01/2001

"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung.

Croyle MA, Chirmule N, Zhang Y, Wilson JM

Journal Of Virology

Publication 5/01/2001

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages.

Zhang Y, Chirmule N, Gao GP, Qian R, Croyle M, Joshi B, Tazelaar J, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 5/01/2001

Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

Schnell MA, Zhang Y, Tazelaar J, Gao GP, Yu QC, Qian R, Chen SJ, Varnavski AN, LeClair C, Raper SE, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 5/01/2001

iNOS expression in dystrophinopathies can be reduced by somatic gene transfer of dystrophin or utrophin.

Louboutin JP, Rouger K, Tinsley JM, Halldorson J, Wilson JM

Molecular Medicine