Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung.
Yang Y, Trinchieri G, Wilson JM
Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+ CTLs in vivo.
Yang Y, Wilson JM
Journal Of Immunology
Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo.
Yang Y, Xiang Z, Ertl HC, Wilson JM
Proceedings Of The National Academy Of Sciences Of The United States Of America
Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses.
Yang Y, Li Q, Ertl HC, Wilson JM
Journal Of Virology
Gene therapy in a xenograft model of cystic fibrosis lung corrects chloride transport more effectively than the sodium defect.
Goldman MJ, Yang Y, Wilson JM