We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

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Publication 10/01/2008

Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain.

Cearley CN, Vandenberghe LH, Parente MK, Carnish ER, Wilson JM, Wolfe JH

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 9/30/2008

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics.

Cideciyan AV, Aleman TS, Boye SL, Schwartz SB, Kaushal S, Roman AJ, Pang JJ, Sumaroka A, Windsor EA, Wilson JM, Flotte TR, Fishman GA, Heon E, Stone EM, Byrne BJ, Jacobson SG, Hauswirth WW

Proceedings Of The National Academy Of Sciences Of The United States Of America

Publication 9/01/2008

Adenovirus-based vaccines generate cytotoxic T lymphocytes to epitopes of NS1 from dengue virus that are present in all major serotypes.

Gao G, Wang Q, Dai Z, Calcedo R, Sun X, Li G, Wilson JM

Human Gene Therapy

Publication 7/01/2008

Impact of preexisting vector immunity on the efficacy of adeno-associated virus-based HIV-1 Gag vaccines.

Lin J, Calcedo R, Vandenberghe LH, Figueredo JM, Wilson JM

Human Gene Therapy

Publication 7/01/2008

HCO3(-) secretion by murine nasal submucosal gland serous acinar cells during Ca2+-stimulated fluid secretion.

Lee RJ, Harlow JM, Limberis MP, Wilson JM, Foskett JK

The Journal Of General Physiology

Publication 5/01/2008

Good news on the clinical gene transfer front.

Wilson JM, Gansbacher B, Berns KI, Bosch F, Kay MA, Naldini L, Wei YQ

Human Gene Therapy