We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 6/10/2001

Differences in the human and mouse amino-terminal leader peptides of ornithine transcarbamylase affect mitochondrial import and efficacy of adenoviral vectors.

Ye X, Zimmer KP, Brown R, Pabin C, Batshaw ML, Wilson JM, Robinson MB

Human Gene Therapy

Publication 3/01/2001

Pharmacologically regulated gene expression in the retina following transduction with viral vectors.

Dejneka NS, Auricchio A, Maguire AM, Ye X, Gao GP, Wilson JM, Bennett J

Gene Therapy

Publication 10/01/2000

Transient depletion of CD4 lymphocyte improves efficacy of repeated administration of recombinant adenovirus in the ornithine transcarbamylase deficient sparse fur mouse.

Ye X, Robinson MB, Pabin C, Batshaw ML, Wilson JM

Gene Therapy

Publication 11/01/1999

Correction of ureagenesis after gene transfer in an animal model and after liver transplantation in humans with ornithine transcarbamylase deficiency.

Batshaw ML, Robinson MB, Ye X, Pabin C, Daikhin Y, Burton BK, Wilson JM, Yudkoff M

Pediatric Research

Publication 7/20/1999

Long-term regulated expression of growth hormone in mice after intramuscular gene transfer.

Rivera VM, Ye X, Courage NL, Sachar J, Cerasoli F Jr, Wilson JM, Gilman M

Proceedings Of The National Academy Of Sciences Of The United States Of America

Publication 4/01/1999

Efficient mitochondrial import of newly synthesized ornithine transcarbamylase (OTC) and correction of secondary metabolic alterations in spf(ash) mice following gene therapy of OTC deficiency.

Zimmer KP, Bendiks M, Mori M, Kominami E, Robinson MB, Ye X, Wilson JM

Molecular Medicine