We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

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Publication 9/01/2013

Mapping the structural determinants responsible for enhanced T cell activation to the immunogenic adeno-associated virus capsid from isolate rhesus 32.33.

Mays LE, Wang L, Tenney R, Bell P, Nam HJ, Lin J, Gurda B, Van Vliet K, Mikals K, Agbandje-McKenna M, Wilson JM

Journal Of Virology

Publication 5/01/2012

Hepatic gene transfer in neonatal mice by adeno-associated virus serotype 8 vector.

Wang L, Wang H, Bell P, McMenamin D, Wilson JM

Human Gene Therapy

Publication 4/01/2012

Sustained correction of OTC deficiency in spf( ash) mice using optimized self-complementary AAV2/8 vectors.

Wang L, Wang H, Morizono H, Bell P, Jones D, Lin J, McMenamin D, Yu H, Batshaw ML, Wilson JM

Gene Therapy

Publication 2/01/2012

Preclinical evaluation of a clinical candidate AAV8 vector for ornithine transcarbamylase (OTC) deficiency reveals functional enzyme from each persisting vector genome.

Wang L, Morizono H, Lin J, Bell P, Jones D, McMenamin D, Yu H, Batshaw ML, Wilson JM

Molecular Genetics And Metabolism

Publication 11/01/2011

Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors.

Wang L, Calcedo R, Bell P, Lin J, Grant RL, Siegel DL, Wilson JM

Human Gene Therapy

Publication 11/01/2011

Inverse zonation of hepatocyte transduction with AAV vectors between mice and non-human primates.

Bell P, Wang L, Gao G, Haskins ME, Tarantal AF, McCarter RJ, Zhu Y, Yu H, Wilson JM

Molecular Genetics And Metabolism