Evaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naive and pre-immunized mice.
Varnavski AN, Calcedo R, Bove M, Gao G, Wilson JM
Efficient transduction of human monocyte-derived dendritic cells by chimpanzee-derived adenoviral vector.
Varnavski AN, Schlienger K, Bergelson JM, Gao GP, Wilson JM
Human Gene Therapy
Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity.
Varnavski AN, Zhang Y, Schnell M, Tazelaar J, Louboutin JP, Yu QC, Bagg A, Gao GP, Wilson JM
Journal Of Virology
Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.
Schnell MA, Zhang Y, Tazelaar J, Gao GP, Yu QC, Qian R, Chen SJ, Varnavski AN, LeClair C, Raper SE, Wilson JM
Molecular Therapy : The Journal Of The American Society Of Gene Therapy