We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 4/01/2003

Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model.

Johnston J, Tazelaar J, Rivera VM, Clackson T, Gao GP, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 6/01/2002

Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity.

Varnavski AN, Zhang Y, Schnell M, Tazelaar J, Louboutin JP, Yu QC, Bagg A, Gao GP, Wilson JM

Journal Of Virology

Publication 1/01/2002

A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency.

Raper SE, Yudkoff M, Chirmule N, Gao GP, Nunes F, Haskal ZJ, Furth EE, Propert KJ, Robinson MB, Magosin S, Simoes H, Speicher L, Hughes J, Tazelaar J, Wivel NA, Wilson JM, Batshaw ML

Human Gene Therapy

Publication 7/01/2001

Systemic IFN-beta gene therapy results in long-term survival in mice with established colorectal liver metastases.

Tada H, Maron DJ, Choi EA, Barsoum J, Lei H, Xie Q, Liu W, Ellis L, Moscioni AD, Tazelaar J, Fawell S, Qin X, Propert KJ, Davis A, Fraker DL, Wilson JM, Spitz FR

The Journal Of Clinical Investigation

Publication 7/01/2001

Intra-arterial delivery of a recombinant adenovirus does not increase gene transfer to tumor cells in a rat model of metastatic colorectal carcinoma.

Maron DJ, Tada H, Moscioni AD, Tazelaar J, Fraker DL, Wilson JM, Spitz FR

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 5/01/2001

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages.

Zhang Y, Chirmule N, Gao GP, Qian R, Croyle M, Joshi B, Tazelaar J, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy