Publication
5/05/2021
Developing a second-generation clinical candidate AAV vector for gene therapy of familial hypercholesterolemia.
Wang L, Muthuramu I, Somanathan S, Zhang H, Bell P, He Z, Yu H, Zhu Y, Tretiakova AP, Wilson JM
Molecular Therapy. Methods & Clinical Development
Publication
1/24/2020
Adenovirus-Antibody Complexes Contributed to Lethal Systemic Inflammation in a Gene Therapy Trial.
Somanathan S, Calcedo R, Wilson JM
Molecular Therapy : The Journal Of The American Society Of Gene Therapy
Publication
12/01/2019
TLR9 signaling mediates adaptive immunity following systemic AAV gene therapy.
Ashley SN, Somanathan S, Giles AR, Wilson JM
Cellular Immunology
Publication
8/08/2018
Mapping an adeno-associated virus 9-specific neutralizing epitope to develop next-generation gene delivery vectors.
Giles AR, Govindasamy L, Somanathan S, Wilson JM
Journal Of Virology
Publication
6/15/2017
Alternative Start Sites Downstream of Non-Sense Mutations Drive Antigen Presentation and Tolerance Induction to C-Terminal Epitopes.
Ashley SN, Somanathan S, Hinderer C, Arias M, McMenamin D, Draper C, Wilson JM
Journal Of Immunology
Publication
2/14/2017
Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency.
Calcedo R, Somanathan S, Qin Q, Betts MR, Rech AJ, Vonderheide RH, Mueller C, Flotte TR, Wilson JM
Proceedings Of The National Academy Of Sciences Of The United States Of America