Publication 5/05/2021

Developing a second-generation clinical candidate AAV vector for gene therapy of familial hypercholesterolemia.

Wang L, Muthuramu I, Somanathan S, Zhang H, Bell P, He Z, Yu H, Zhu Y, Tretiakova AP, Wilson JM

Molecular Therapy. Methods & Clinical Development

Publication 1/24/2020

Adenovirus-Antibody Complexes Contributed to Lethal Systemic Inflammation in a Gene Therapy Trial.

Somanathan S, Calcedo R, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 12/01/2019

TLR9 signaling mediates adaptive immunity following systemic AAV gene therapy.

Ashley SN, Somanathan S, Giles AR, Wilson JM

Cellular Immunology

Publication 8/08/2018

Mapping an adeno-associated virus 9-specific neutralizing epitope to develop next-generation gene delivery vectors.

Giles AR, Govindasamy L, Somanathan S, Wilson JM

Journal Of Virology

Publication 6/15/2017

Alternative Start Sites Downstream of Non-Sense Mutations Drive Antigen Presentation and Tolerance Induction to C-Terminal Epitopes.

Ashley SN, Somanathan S, Hinderer C, Arias M, McMenamin D, Draper C, Wilson JM

Journal Of Immunology

Publication 2/14/2017

Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency.

Calcedo R, Somanathan S, Qin Q, Betts MR, Rech AJ, Vonderheide RH, Mueller C, Flotte TR, Wilson JM

Proceedings Of The National Academy Of Sciences Of The United States Of America