Publication 7/09/2018 Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol. Wang L, Smith J, Breton C, Clark P, Zhang J, Ying L, Che Y, Lape J, Bell P, Calcedo R, Buza EL, Saveliev A, Bartsevich VV, He Z, White J, Li M, Jantz D, Wilson JM Nature Biotechnology