We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 1/01/2010

The pleiotropic effects of natural AAV infections on liver-directed gene transfer in macaques.

Wang L, Calcedo R, Wang H, Bell P, Grant R, Vandenberghe LH, Sanmiguel J, Morizono H, Batshaw ML, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 9/01/2009

Adeno-associated virus-mediated gene transfer to nonhuman primate liver can elicit destructive transgene-specific T cell responses.

Gao G, Wang Q, Calcedo R, Mays L, Bell P, Wang L, Vandenberghe LH, Grant R, Sanmiguel J, Furth EE, Wilson JM

Human Gene Therapy

Publication 12/01/2008

Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat.

Bish LT, Morine K, Sleeper MM, Sanmiguel J, Wu D, Gao G, Wilson JM, Sweeney HL

Human Gene Therapy

Publication 12/01/2008

Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines.

Bish LT, Sleeper MM, Brainard B, Cole S, Russell N, Withnall E, Arndt J, Reynolds C, Davison E, Sanmiguel J, Wu D, Gao G, Wilson JM, Sweeney HL

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 12/01/2008

Percutaneous Transendocardial Delivery of Self-complementary Adeno-associated Virus 6 Achieves Global Cardiac Gene Transfer in Canines.

Bish LT, Sleeper MM, Brainard B, Cole S, Russell N, Withnall E, Arndt J, Reynolds C, Davison E, Sanmiguel J, Wu D, Gao G, Wilson JM, Lee Sweeney H

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 5/02/2007

Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent.

Lebherz C, Sanmiguel J, Wilson JM, Rader DJ

Cardiovascular Diabetology