We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 12/01/2005

Creatine kinase, a magnetic resonance-detectable marker gene for quantification of liver-directed gene transfer.

Li Z, Qiao H, Lebherz C, Choi SR, Zhou X, Gao G, Kung HF, Rader DJ, Wilson JM, Glickson JD, Zhou R

Human Gene Therapy

Publication 5/01/2005

Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRalpha.

Lehrke M, Lebherz C, Millington SC, Guan HP, Millar J, Rader DJ, Wilson JM, Lazar MA

Cell Metabolism

Publication 3/01/2005

Complete deficiency of the low-density lipoprotein receptor is associated with increased apolipoprotein B-100 production.

Millar JS, Maugeais C, Ikewaki K, Kolansky DM, Barrett PH, Budreck EC, Boston RC, Tada N, Mochizuki S, Defesche JC, Wilson JM, Rader DJ

Arteriosclerosis, Thrombosis, And Vascular Biology

Publication 9/01/2000

Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor.

Chen SJ, Rader DJ, Tazelaar J, Kawashiri M, Gao G, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 2/01/1996

Safety and feasibility of liver-directed ex vivo gene therapy for homozygous familial hypercholesterolemia.

Raper SE, Grossman M, Rader DJ, Thoene JG, Clark BJ 3rd, Kolansky DM, Muller DW, Wilson JM

Annals Of Surgery

Publication 11/01/1995

A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia.

Grossman M, Rader DJ, Muller DW, Kolansky DM, Kozarsky K, Clark BJ 3rd, Stein EA, Lupien PJ, Brewer HB Jr, Raper SE

Nature Medicine