Publication
5/01/2014
The structure of AAVrh32.33, a novel gene delivery vector.
Mikals K, Nam HJ, Van Vliet K, Vandenberghe LH, Mays LE, McKenna R, Wilson JM, Agbandje-McKenna M
Journal Of Structural Biology
Publication
1/01/2014
AAV8 induces tolerance in murine muscle as a result of poor APC transduction, T cell exhaustion, and minimal MHCI upregulation on target cells.
Mays LE, Wang L, Lin J, Bell P, Crawford A, Wherry EJ, Wilson JM
Molecular Therapy : The Journal Of The American Society Of Gene Therapy
Publication
9/01/2013
Mapping the structural determinants responsible for enhanced T cell activation to the immunogenic adeno-associated virus capsid from isolate rhesus 32.33.
Mays LE, Wang L, Tenney R, Bell P, Nam HJ, Lin J, Gurda B, Van Vliet K, Mikals K, Agbandje-McKenna M, Wilson JM
Journal Of Virology
Publication
1/01/2011
The complex and evolving story of T cell activation to AAV vector-encoded transgene products.
Mays LE, Wilson JM
Molecular Therapy : The Journal Of The American Society Of Gene Therapy
Publication
12/01/2009
Identification of the murine AAVrh32.33 capsid-specific CD8+ T cell epitopes.
Mays LE, Wilson JM
The Journal Of Gene Medicine
Publication
5/15/2009
Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins.
Mays LE, Vandenberghe LH, Xiao R, Bell P, Nam HJ, Agbandje-McKenna M, Wilson JM
Journal Of Immunology