Publication
12/05/2018
Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function.
Giles AR, Sims JJ, Turner KB, Govindasamy L, Alvira MR, Lock M, Wilson JM
Molecular Therapy : The Journal Of The American Society Of Gene Therapy
Publication
11/04/2015
Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin.
Wang Q, Lock M, Prongay AJ, Alvira MR, Petkov B, Wilson JM
Molecular Therapy. Methods & Clinical Development
Publication
4/01/2014
Absolute determination of single-stranded and self-complementary adeno-associated viral vector genome titers by droplet digital PCR.
Lock M, Alvira MR, Chen SJ, Wilson JM
Human Gene Therapy Methods
Publication
12/01/2013
Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia.
Chen SJ, Sanmiguel J, Lock M, McMenamin D, Draper C, Limberis MP, Kassim SH, Somanathan S, Bell P, Johnston JC, Rader DJ, Wilson JM
Human Gene Therapy. Clinical Development
Publication
2/01/2012
Analysis of particle content of recombinant adeno-associated virus serotype 8 vectors by ion-exchange chromatography.
Lock M, Alvira MR, Wilson JM
Human Gene Therapy Methods
Publication
10/01/2010
Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale.
Lock M, Alvira M, Vandenberghe LH, Samanta A, Toelen J, Debyser Z, Wilson JM
Human Gene Therapy