Publication 12/05/2018

Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function.

Giles AR, Sims JJ, Turner KB, Govindasamy L, Alvira MR, Lock M, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 11/04/2015

Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin.

Wang Q, Lock M, Prongay AJ, Alvira MR, Petkov B, Wilson JM

Molecular Therapy. Methods & Clinical Development

Publication 4/01/2014

Absolute determination of single-stranded and self-complementary adeno-associated viral vector genome titers by droplet digital PCR.

Lock M, Alvira MR, Chen SJ, Wilson JM

Human Gene Therapy Methods

Publication 12/01/2013

Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia.

Chen SJ, Sanmiguel J, Lock M, McMenamin D, Draper C, Limberis MP, Kassim SH, Somanathan S, Bell P, Johnston JC, Rader DJ, Wilson JM

Human Gene Therapy. Clinical Development

Publication 2/01/2012

Analysis of particle content of recombinant adeno-associated virus serotype 8 vectors by ion-exchange chromatography.

Lock M, Alvira MR, Wilson JM

Human Gene Therapy Methods

Publication 10/01/2010

Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale.

Lock M, Alvira M, Vandenberghe LH, Samanta A, Toelen J, Debyser Z, Wilson JM

Human Gene Therapy