We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 11/01/2017

Wnt10b and Dkk-1 gene therapy differentially influenced trabecular bone architecture, soft tissue integrity, and osteophytosis in a skeletally mature rat model of osteoarthritis.

Mason JB, Gurda BL, Hankenson KD, Harper LR, Carlson CS, Wilson JM, Richardson DW

Connective Tissue Research

Publication 1/01/2017

Delivery and evaluation of recombinant adeno-associated viral vectors in the equine distal extremity for the treatment of laminitis.

Mason JB, Gurda BL, Van Wettere A, Engiles JB, Wilson JM, Richardson DW

Equine Veterinary Journal

Publication 2/01/2016

Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII.

Gurda BL, De Guilhem De Lataillade A, Bell P, Zhu Y, Yu H, Wang P, Bagel J, Vite CH, Sikora T, Hinderer C, Calcedo R, Yox AD, Steet RA, Ruane T, O'Donnell P, Gao G, Wilson JM, Casal M, Ponder KP, Haskins ME

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 8/01/2015

Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates.

Hinderer C, Bell P, Louboutin JP, Zhu Y, Yu H, Lin G, Choa R, Gurda BL, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Tarantal AF, Casal ML, Haskins ME, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 12/01/2014

Intrathecal gene therapy corrects CNS pathology in a feline model of mucopolysaccharidosis I.

Hinderer C, Bell P, Gurda BL, Wang Q, Louboutin JP, Zhu Y, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Haskins ME, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 10/14/2014

Liver-directed gene therapy corrects cardiovascular lesions in feline mucopolysaccharidosis type I.

Hinderer C, Bell P, Gurda BL, Wang Q, Louboutin JP, Zhu Y, Bagel J, O'Donnell P, Sikora T, Ruane T, Wang P, Haskins ME, Wilson JM

Proceedings Of The National Academy Of Sciences Of The United States Of America