We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 4/01/2015

Motor neuron transduction after intracisternal delivery of AAV9 in a cynomolgus macaque.

Bell P, Hinderer C, Louboutin JP, Yu H, Grant R, Bote E, Wilson JM

Human Gene Therapy Methods

Publication 12/10/2014

Widespread gene transfer in the central nervous system of cynomolgus macaques following delivery of AAV9 into the cisterna magna.

Hinderer C, Bell P, Vite CH, Louboutin JP, Grant R, Bote E, Yu H, Pukenas B, Hurst R, Wilson JM

Molecular Therapy. Methods & Clinical Development

Publication 8/01/2014

Increased mucosal CD4+ T cell activation in rhesus macaques following vaccination with an adenoviral vector.

Bukh I, Calcedo R, Roy S, Carnathan DG, Grant R, Qin Q, Boyd S, Ratcliffe SJ, Veeder CL, Bellamy SL, Betts MR, Wilson JM

Journal Of Virology

Publication 1/01/2013

AAV9 targets cone photoreceptors in the nonhuman primate retina.

Vandenberghe LH, Bell P, Maguire AM, Xiao R, Hopkins TB, Grant R, Bennett J, Wilson JM

Plos One

Publication 6/22/2011

Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey.

Vandenberghe LH, Bell P, Maguire AM, Cearley CN, Xiao R, Calcedo R, Wang L, Castle MJ, Maguire AC, Grant R, Wolfe JH, Wilson JM, Bennett J

Science Translational Medicine

Publication 1/01/2010

The pleiotropic effects of natural AAV infections on liver-directed gene transfer in macaques.

Wang L, Calcedo R, Wang H, Bell P, Grant R, Vandenberghe LH, Sanmiguel J, Morizono H, Batshaw ML, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy