Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice.
Skorupa AF, Fisher KJ, Wilson JM, Parente MK, Wolfe JH
Persistent transgene product in retina, optic nerve and brain after intraocular injection of rAAV.
Dudus L, Anand V, Acland GM, Chen SJ, Wilson JM, Fisher KJ, Maguire AM, Bennett J
Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibers.
Jooss K, Yang Y, Fisher KJ, Wilson JM
Journal Of Virology
Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus.
Herzog RW, Hagstrom JN, Kung SH, Tai SJ, Wilson JM, Fisher KJ, High KA
Proceedings Of The National Academy Of Sciences Of The United States Of America
Recombinant adeno-associated virus for muscle directed gene therapy.
Fisher KJ, Jooss K, Alston J, Yang Y, Haecker SE, High K, Pathak R, Raper SE, Wilson JM
The transmembrane domain of diphtheria toxin improves molecular conjugate gene transfer.
Fisher KJ, Wilson JM
The Biochemical Journal