We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 3/01/2009

Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing.

Song Y, Lou HH, Boyer JL, Limberis MP, Vandenberghe LH, Hackett NR, Leopold PL, Wilson JM, Crystal RG

Human Gene Therapy

Publication 3/01/2007

Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 rhesus macaque-derived adeno-associated virus vector.

Sondhi D, Hackett NR, Peterson DA, Stratton J, Baad M, Travis KM, Wilson JM, Crystal RG

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 8/01/2006

A common mechanism for cytoplasmic dynein-dependent microtubule binding shared among adeno-associated virus and adenovirus serotypes.

Kelkar S, De BP, Gao G, Wilson JM, Crystal RG, Leopold PL

Journal Of Virology

Publication 1/01/2006

High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses.

De BP, Heguy A, Hackett NR, Ferris B, Leopold PL, Lee J, Pierre L, Gao G, Wilson JM, Crystal RG

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 10/01/2005

Induction of protective immunity to anthrax lethal toxin with a nonhuman primate adenovirus-based vaccine in the presence of preexisting anti-human adenovirus immunity.

Hashimoto M, Boyer JL, Hackett NR, Wilson JM, Crystal RG

Infection And Immunity

Publication 4/25/2005

Identification of murine CD8 T cell epitopes in codon-optimized SARS-associated coronavirus spike protein.

Zhi Y, Kobinger GP, Jordan H, Suchma K, Weiss SR, Shen H, Schumer G, Gao G, Boyer JL, Crystal RG, Wilson JM

Virology