We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

Publication 5/01/2001

"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung.

Croyle MA, Chirmule N, Zhang Y, Wilson JM

Journal Of Virology

Publication 5/01/2001

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages.

Zhang Y, Chirmule N, Gao GP, Qian R, Croyle M, Joshi B, Tazelaar J, Wilson JM

Molecular Therapy : The Journal Of The American Society Of Gene Therapy

Publication 1/20/2001

Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies.

Cordier L, Gao GP, Hack AA, McNally EM, Wilson JM, Chirmule N, Sweeney HL

Human Gene Therapy

Publication 10/10/2000

Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo.

Gao G, Qu G, Burnham MS, Huang J, Chirmule N, Joshi B, Yu QC, Marsh JA, Conceicao CM, Wilson JM

Human Gene Therapy

Publication 9/01/2000

CD40 ligand-dependent activation of cytotoxic T lymphocytes by adeno-associated virus vectors in vivo: role of immature dendritic cells.

Zhang Y, Chirmule N, Gao Gp, Wilson J

Journal Of Virology

Publication 4/01/2000

Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40-CD40 ligand interactions.

Chirmule N, Raper SE, Burkly L, Thomas D, Tazelaar J, Hughes JV, Wilson JM

Journal Of Virology