We invite you to discover Human Gene Therapy Clinical Development, a peer-reviewed journal publishing preclinical research and clinical trial data for gene and cell therapies.

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Publication 8/01/2014

Increased mucosal CD4+ T cell activation in rhesus macaques following vaccination with an adenoviral vector.

Bukh I, Calcedo R, Roy S, Carnathan DG, Grant R, Qin Q, Boyd S, Ratcliffe SJ, Veeder CL, Bellamy SL, Betts MR, Wilson JM

Journal Of Virology

Publication 12/01/2013

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression.

Mueller C, Chulay JD, Trapnell BC, Humphries M, Carey B, Sandhaus RA, McElvaney NG, Messina L, Tang Q, Rouhani FN, Campbell-Thompson M, Fu AD, Yachnis A, Knop DR, Ye GJ, Brantly M, Calcedo R, Somanathan S, Richman LP, Vonderheide RH, Hulme MA, Brusko TM, Wilson JM, Flotte TR

The Journal Of Clinical Investigation

Publication 10/18/2013

Humoral Immune Response to AAV.

Calcedo R, Wilson JM

Frontiers In Immunology

Publication 9/01/2013

Self-reactive CFTR T cells in humans: implications for gene therapy.

Calcedo R, Griesenbach U, Dorgan DJ, Soussi S, Boyd AC, Davies JC, Higgins TE, Hyde SC, Gill DR, Innes JA, Porteous DJ, Alton EW, Wilson JM, Limberis MP

Human Gene Therapy. Clinical Development

Publication 2/01/2013

Gene therapy for mucopolysaccharidosis type VI is effective in cats without pre-existing immunity to AAV8.

Ferla R, O'Malley T, Calcedo R, O'Donnell P, Wang P, Cotugno G, Claudiani P, Wilson JM, Haskins M, Auricchio A

Human Gene Therapy

Publication 11/01/2011

Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors.

Wang L, Calcedo R, Bell P, Lin J, Grant RL, Siegel DL, Wilson JM

Human Gene Therapy